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  • rypz79
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    Post count: 33

    Dr. Corenman

    AFAIU I’m dealing with several indirectly connected issues that are stemming from the same source – DDD:
    1. Discogenic pain
    2. Facet joint syndrome
    3. Spine instability
    4. Nerve pressure/damage

    Again according to date medical knowledge  there is no guarantee that even If I go for a TLIF surgery there will be an additional improvement with problem #4 but it will solve probelm #1 and prevent problems #2 & 3. am I right?

    Total disc replacements (TDR) or “arthroplasty-ADR” works well in the neck but are not very good in the lower back

    In general, why? because it doesn’t solve “posterior issues“ such as spine stability and facet joint syndrome?
    Common sense says tells me that if you restore the disc space to it’s previous state it also decompress the foraminal space reliving the stenosis and the exiting pinched nerve on this level.

    According to this brochure
    There is a surgery called Total Lumbar Facet Replacement which uses a newly TOPS or NEXUX artificial joint systems that stables the facet joints function while preserving motion.

    Now the question I’m asking is if you add TLFR does it (at least it theoretically) solve the problems you presented with having a TDR: 

    ….redo decompression to free the nerve. This procedure might require removing significant facet bony mass which could make the facet incompetent. An intact and functioning facet is necessary to allow a TDR to function properly.

    Thank You very much Dr. Corenman

    rypz79
    Participant
    Post count: 33

    Dr. Corenman

    This is a summary of the Radiologist on the MRI check I did on the 12/18/2020:

    The test was performed on sagittal and axial planes in the STIR, T2, T1 series and DIXON reconstructions w/ & w/o gadolinium IV injection.

    Reason for referral: Still pain while stepping and foot paresthesia 8 months after forminotomy and discectomy at height L5-S1 on the right. 

    In comparison from MRI dated 12/17/2019:
    Findings:

    ……

    L4-L5: Slight lowering of the disc. Diffuse disc bulge causes slight pressure on the spinal canal, slight bilateral stenosis on neural foramen, slight pressure on the L4 neural root.

    L5-S1: Right para-median and foraminal disc herniation.  Narrowing of the right neural foramen and pressure on the L5 neural root.

    The findings appear to have no significant change from the previous test. There is a lowering of the disc.

    After a gadolinium injection there is a Contrast Medium Enhancement (CME) of the:
    [] Interspinous ligaments at level L4-L5
    [] Facet joints at levels L4-L5, L5-S1
    [] Surgical tract in the forminotomy area at  level L5-S1 on the right

    Conclusions:
    There is still narrowing of neural formina at level L5-S1 and pressure on the L5 neural root both on the right

    I’m 11 months post-op there is much improvement in the sensation still there are symptoms of stabbing needls and electric shock and it is painful to walk distances especially if you are wearing tight/slim/unstable shoes , the sole is still numb on the foot balls but there is more sensation heat/cold threshold are up compared to the healthy one. My back is sore I feel like “sitting on eggs” every wrong movement can light it up classic discogenic pain. I need to change postures frequently and take NSAIDs as well a 300mg of Pregabalin daily. As the results say I feel that the nerve root is not fully free and it’s affecting both it’s healing and day to day condition.
    I have 1 year post-op on appointment with the surgeon at beginning of March.

    My questions are:

    1) What we can conclude from these MRI findings? Are the MCEs a direct consequence of improper disc space or height which results in a chronic inflammation?

    2) recently I’ve been studying about an artificial (sometimes called total) Disc Replacement procedure. The specific prosthesis is called M6-L by Spinalkinetics. Unfortunately it’s not done were I live (I’ll have to question the surgeon to make sure though) and it’s very expensive abroad ~40k$. 

    What do you know about these DR procedures? Do you it’s the best solution for one level LDH to those who still want to have active lifestyle in contrast to disc fusion were the back’s mobility & flexibility is impaired and the pressure goes up to the previous level in my case L4-5 which also starting show signs of wear and tear.

    Thank You
    Roey

    rypz79
    Participant
    Post count: 33

    Dr. Corenman,

    what is the recovery methodology for afferent neurons in cases of axonal death and some myelin damage distal to place of injury? i.e how CAN they recover from such long distance with relatively short time?

    I did not questioned it right.
    I meant how can I feel some improvement with only 6 months gone by?
    Is there a “critical mass” of connected neurons from which the nerve becomes “non-irritable”?

    By asking about CAN & Methodolgy I meant about a gradual improvement as opposed to connected/not conneted (on/off) situation I understood from your articles.
    Improvement that is some shrinkage in the numb area and less irritation (it takes more time to provoke it).

    I’ve read a bit and found out that the 1 mm/day or 1 inch/month is a thumb rule first detailed in “Rate of regeneration of peripheral nerves in man” HJ Seddon et al. J Physiol. 1943. (p191-215)” In “Nerve Regeneration: Tissue Engineering Strategies (2006)” Recknor JB and Mallapragada SK cited that “Human axon growth rates can reach 2 mm/day in small nerves and 5 mm/day in large nerves.” So I guess there are several factors involved here and the axon growth rate is not a constant number.
    From your clinical experience what is more accurate in lumbar radiculopathy cases ?(nerve root->sciatic nerve->terminal branches)

    Two more questions in your permission:
    1) Can the wallerian degeneration process have already started in the distal segment several days/weeks after the LDH together with the denevration process from the proximal segment? 
    2) Can TENS treatments promote PN regeneration or mitigate “nerve irritability” symptoms? modernneuropathy.com/5-best-e-stimulation-devices-for-nerve-regeneration/

    The buttom line is that it’s more harder for mentally then physically those irritations & limitations increase my level of anxiety and depression and can cause me panic attacks.
    I could’ve handle the burning, numbess & pain much better if I only knew that this is a residual phase for a relative short time frame (upto a year or so post-op) after which the nerve will become “stable” or asymptomatic without allodynia pathological lines.
    I can live with numb patches and/or some loss of sensation thresholds.

    Thank you very much Dr. Corenman

    rypz79
    Participant
    Post count: 33

    Dr. Corenman,

    I miss calculated the post-op time. on 25th it will be 6 months.

    I’ve written about my numb skin just to describe to anyone who doesn’t have numbness how it feels like but I guess it wasn’t good analogy.
    I think the best way I can describe it is walking on a blister or on a bubble it feels like dead skin.
    When walking outside this “bubble” spreads along the the whole sole and to recover from the soreness it produces almost instantly you to need to rest preferably with your leg up.
    I think I’m making mistake comparing my right foot to the healthy left one but on the other hand I cannot tell what is a “normal” foot feels like.

    Hypersensitivity of the skin (hyperalgesia or allodynia) can occur. A simple brushing of bed sheets on exposed skin can cause intense pain.

    No I don’t think I qualify for allodynia, thermal or mechanical. When I said alternates I meant “when it’s painful the pain feeling alternates”…it’s not always painful.
    In saying numb/numbness I mean loss of sensation not lack of sensation. The threshold for hot/cold sensation is 70-80% of the other foot that’s fair I can live with that.

    Putting all my body weight on my foot balls (standing on my toes in point position) for a period of time will aggravate the nerve there is no such problem in the other foot. It also applies for prolonged sitting leg-over-leg (only for right over left) and for walking distances. The accumulated pressure on the balls of the foot or on their nerve path is currently limited and symptomatic (causes soreness and some burning sensation along the whole sole)

    I think I’m doing a little bit better on Idle state the numbness/bubble has shrunk to the area beneath my big toe ball. There are less flairups (i.e feeling of burning feet) after prolonged sitting or walking, but still it’s not asymptomatic (I’ve heard many peopole with lower somatosensoric nerve issues that their sole is just numb, they don’t feel anything) and draws my mind’s attention regularly. also sometimes I feel a little bit of tingling on the dorsum of the foot though it still feels numb the sensations hot/cold/touch feels normal.

    I’ve been put on pregabalin (started 75mgx2 /day then after a week 150×2 /day) I really hope it’s temporary and not the real cause of my improvement so I won’t use this medication on a regular basis for the long run.

    I’ve measured the distance from the L5 exit (I have a scar there) through the thigh⋚ till the end of the foot it’s roughly 4’1 (I’m 6’1) so if the nerve recovers at 1mm per day it will take it almost 3.5 years to get there seems highly unlikeabke. Like you’ve written and said those wallerian degeneration are generally preserved (may I add exclusively?) for effernt neurons recovery.

    If so then what is the recovery methodology for afferent neurons in cases of axonal death and some myelin damage distal to place of injury? i.e how CAN they recover from such long distance with relatively short time ?

    Thank you Dr. Corenman

    rypz79
    Participant
    Post count: 33

    Hello Dr. Corenman,

    I’m now ~6 Months post-op , still got loss of sensation (I can best describe it as touching something with a burned blistered skin) in the area of the balls of the foot which alternates with stabing pain & soreness in the same area.

    The dorsum of the foot also feels somewhat numb (though it’s sensitive to touch heat/cold)
    IDK but I think the two are connected though the latter doesn’t bother me at all.

    Now what has happened is I started to feel my lowerback sometimes it feels stiff and sometimes it feels like burning and itching in the area of the surgery. I cannot sit prolonged times or with my right leg over the left one or lie free on my right side. I think It’s flaring the nerve. That’s so exhausting and irritating mentally and physically to have to deal with postures and time to get up to sit down. 1 year ago I sat or lied down how I wanted when I wanted.

    Bought an inversion table to further decompress my spine and I’m also carefully dead-lifting 45lbs it’s really the best way to strengthen those lower back muscles.

    3 Q’s in your permission:

    1) Does strengthening those lower back muscles will help me sit prolonged times without having back pain? if so how do I know when they are strong enough?

    2) Does inversion/traction therphy helps (maybe indirectly) in the nerve regeneration process by increasing the intervertebral space i.e the more room it has the more it can heal?

    3) Is the prognosis of Axonotmesis “usually good in terms of recovery. Rate of recovery depends on the distance from the site of injury, and axonal regeneration can go up to 1 inch per month. Complete recovery can take anywhere from 6 months to a year” is valid in my case also? I still got to go six more months (at most) to complete the recovery process?

    Thank you so much Dr. Corenman

    rypz79
    Participant
    Post count: 33

    Hello Dr. Corenman,

    4.5 months post-op I think things are starting to improve a bit. I can walk almost without pain for some distance but there could be a flare-up here and there it’s not normal 100%.

    My primary physician (not the surgeon) sent me to do an EMG+NCT test and as you predicted in your article for these situations the answer was negative “there is no indication for foot neuropathy or right lumabar radiculopathy”.

    The problem I’m facing now is that I still cannot put much pressure on the sole of the foot barefoot toe-tips even without weights start causing me pain and numbness in the area of contact with the floor.

    I need/want to strengthen my quads the muscles around the knee and the gastrocnemius muscles should I persist with the pressure going through the neuropathic pain (there is no other way to work these muscles) or wait with it and stop at any signal of pain?

    Thank you very much Dr. Corenman

Viewing 6 posts - 13 through 18 (of 32 total)