Viewing 6 posts - 13 through 18 (of 19 total)
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  • exercise453
    Member
    Post count: 53

    Dear Doctor,

    Rising liver enzymes have become an issue.

    For 2-3 years I’ve taken Ultram 125mg daily 1 x 75 1×50
    Gabrapentin 800mg daily 2 x 400
    Advil 800mg daily 1 x 800

    The symptoms from a fall and 2 weight lifting injuries have damaged the spine from c2-3 thru c7-t1 with each trauma claiming its own area. As I remain functional and grudgingly “active” the medication is for chronic symptoms of nerve, disc, facet, arthritis, and pain (no myelopathy…..yet). I have studied the spine upwards of 2500 hours, the last 1000 with you.

    To attempt to lower liver enzymes I have eliminated advil but I wonder:

    Is any of these three medications (or two) easier on the liver than the others???
    Am I eliminating the right one for the symptoms described???
    Is this assortment redundant???
    Is this amount of medication in a 65 year old man unusual to drive up liver functions???
    Is there any suggestion you would make with the liver enzymes in mind???

    (As I have mentioned before, what you are doing is unheard of. Who knows how many thousands or tens of thousands of people you have selflessly educated and helped. Deep down I know my last stop is you.)

    Thanks

    Donald Corenman, MD, DC
    Moderator
    Post count: 8660

    Liver damage can typically occur with Tylenol products but on rare circumstances, NSAIDs can also cause liver injury. Normally, the dose of Tylenol (found in Ultram) has to be greater than 3000mg/day but certain patients may be more sensitive than that for a lower dose.

    Gabapentin would be very unusual to be the cause but there are case reports in the literature.

    One 800mg Advil should not cause liver injury but again, every individual has a different biochemical makeup.

    There are many different disorders that can cause liver damage that are not all related to medications. You should consult a hepatologist (liver specialist) to have a full work-up.

    Dr. Corenman

    PLEASE REMEMBER, THIS FORUM IS MEANT TO PROVIDE GENERAL INFORMATION ON SPINE ANATOMY, CONDITIONS AND TREATMENTS. TO GET AN ACCURATE DIAGNOSIS, YOU MUST VISIT A QUALIFIED PROFESSIONAL IN PERSON.
     
    Donald Corenman, MD, DC is a highly-regarded spine surgeon, considered an expert in the area of neck and back pain. Trained as both a Medical Doctor and Doctor of Chiropractic, Dr. Corenman earned academic appointments as Clinical Assistant Professor and Assistant Professor of Orthopaedic Surgery at the University of Colorado Health Sciences Center, and his research on spine surgery and rehabilitation has resulted in the publication of multiple peer-reviewed articles and two books.
    exercise453
    Member
    Post count: 53

    Dear Dr,

    I do monitor liver enzymes regularly. I did not mean I had liver damage but a spike in enzymes. I had a spike last year, reduced advil and they returned to normal. Now I have reluctantly eliminated advil totally, and seem to be able to survive without it. The enzymes will be checked in a month or so and I think (hope) they will return to normal. I see the literature implicates anti inflammatory and these seizure medications as possible causes of elevated liver enzymes.

    On another note, just one question. Does anything with myelopathy or “mild to moderate compression of the thecal sac” or anything else with the cervical or upper thoracic spine cause low grade fever???

    Thanks

    Donald Corenman, MD, DC
    Moderator
    Post count: 8660

    Cord compression or myelopathy will not cause low grade fevers.

    Dr. Corenman

    PLEASE REMEMBER, THIS FORUM IS MEANT TO PROVIDE GENERAL INFORMATION ON SPINE ANATOMY, CONDITIONS AND TREATMENTS. TO GET AN ACCURATE DIAGNOSIS, YOU MUST VISIT A QUALIFIED PROFESSIONAL IN PERSON.
     
    Donald Corenman, MD, DC is a highly-regarded spine surgeon, considered an expert in the area of neck and back pain. Trained as both a Medical Doctor and Doctor of Chiropractic, Dr. Corenman earned academic appointments as Clinical Assistant Professor and Assistant Professor of Orthopaedic Surgery at the University of Colorado Health Sciences Center, and his research on spine surgery and rehabilitation has resulted in the publication of multiple peer-reviewed articles and two books.
    exercise453
    Member
    Post count: 53

    Dear Dr

    If you forget about the diagnostic value of the cervical SNRB and eliminate the anesthetic would the regular cervical epidural steroid injection performed thru C7-T1 put more, less, or the same amount of steroid on the left C7-T1 (C8) nerve root???

    Would the regular cervical epidural steroid injection performed thru C7-T1 get the steroid on the T1 nerve root below???

    Thank You as always

    Donald Corenman, MD, DC
    Moderator
    Post count: 8660

    Yes- the SNRB will place about the same amount of medication on the C8 nerve as an epidural steroid injection will at the same level.

    Dr. Corenman

    PLEASE REMEMBER, THIS FORUM IS MEANT TO PROVIDE GENERAL INFORMATION ON SPINE ANATOMY, CONDITIONS AND TREATMENTS. TO GET AN ACCURATE DIAGNOSIS, YOU MUST VISIT A QUALIFIED PROFESSIONAL IN PERSON.
     
    Donald Corenman, MD, DC is a highly-regarded spine surgeon, considered an expert in the area of neck and back pain. Trained as both a Medical Doctor and Doctor of Chiropractic, Dr. Corenman earned academic appointments as Clinical Assistant Professor and Assistant Professor of Orthopaedic Surgery at the University of Colorado Health Sciences Center, and his research on spine surgery and rehabilitation has resulted in the publication of multiple peer-reviewed articles and two books.
Viewing 6 posts - 13 through 18 (of 19 total)
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