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What is the risk ? It is still contained within the cage, correct ?
sorry for all the questions. I am researching use of BMP with MIS TLIF and have come across a few cases with
neuroforaminal overgrowth.1.) How is this possible to have radiculopathy and neroformanial bone growth after MIS TLIF with BMP vs. Open TLIF with BMP, especially when BMP is used on the non TLIF side with open TLIF ? MIS TLIF has not posterolateral fusion.
2.) Where is the BMP placed in MIS TLIF ? In the cage, in front of cage ?
3.) Aren’t there bone chips packed in the disc space to protect the BMP from growing out with either surgery ?
Thank you!
I had found that placing BMP in the cage itself created the potential for a seroma as BMP is designed to be inflammatory. Even though the seroma was rare, the ones that occurred would have to be addressed with an aspiration and injection. Occasionally even a second surgery to evacuate the seroma was needed.
Sequestering the BMP in the disc space with barriers (Mastergraft and the cage itself) prevented these seromas for the most part.
Placing the BMP in the lateral gutter (the area of the facet and transverse process) never allowed the seroma to occur. This is most likely due to the nature of this area (a trough that cradled the BMP/bone graft) and was covered by muscle (when the retraction was removed, the muscle “sprung back” and sealed the BMP in a muscle barrier).
Whether mini-open TLIF or MIS TLIF, there is no “standard” way to place the BMP. It can be places wherever the surgeon wants it to go.
Dr. Corenman
PLEASE REMEMBER, THIS FORUM IS MEANT TO PROVIDE GENERAL INFORMATION ON SPINE ANATOMY, CONDITIONS AND TREATMENTS. TO GET AN ACCURATE DIAGNOSIS, YOU MUST VISIT A QUALIFIED PROFESSIONAL IN PERSON.
Donald Corenman, MD, DC is a highly-regarded spine surgeon, considered an expert in the area of neck and back pain. Trained as both a Medical Doctor and Doctor of Chiropractic, Dr. Corenman earned academic appointments as Clinical Assistant Professor and Assistant Professor of Orthopaedic Surgery at the University of Colorado Health Sciences Center, and his research on spine surgery and rehabilitation has resulted in the publication of multiple peer-reviewed articles and two books.I know you research MIS TLIF.
There are reports of neuroforaminal bone growth from just putting BMP in the cage within the disc space; unless I am reading this wrong.
How is this possible to have radiculopathy and neroformanial bone growth after MIS TLIF with BMP ?
MIS TLIF has no posterolateral fusion.
MIS TLIF generally has no posterolateral fusion (PLF). The PLF is not related to neuroforaminal bone growth as the BMP is in the latter gutter-not contiguous with the nerve canal.
Radiculopathy and heterotopic ossification (bone formation where it does not belong) can occur with the TLIF procedure whether MIS or not. It has nothing to do with PLF. I have seen radiculopathy and heterotopic ossification in TLIFs without BMP and of course with BMP. I believe that the positioning and sequestration of the BMP as I noted before is the key to prevent heterotopic ossification.
Dr. Corenman
PLEASE REMEMBER, THIS FORUM IS MEANT TO PROVIDE GENERAL INFORMATION ON SPINE ANATOMY, CONDITIONS AND TREATMENTS. TO GET AN ACCURATE DIAGNOSIS, YOU MUST VISIT A QUALIFIED PROFESSIONAL IN PERSON.
Donald Corenman, MD, DC is a highly-regarded spine surgeon, considered an expert in the area of neck and back pain. Trained as both a Medical Doctor and Doctor of Chiropractic, Dr. Corenman earned academic appointments as Clinical Assistant Professor and Assistant Professor of Orthopaedic Surgery at the University of Colorado Health Sciences Center, and his research on spine surgery and rehabilitation has resulted in the publication of multiple peer-reviewed articles and two books. -
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